Low-Molecular-Weight Heparin vs Heparin in the Treatment of Patients With Pulmonary Embolism

Low-Molecular-Weight Heparin vs Heparin in the Treatment of Patients With Pulmonary Embolism

Results: Of 200 patients with high-probability lung scan findings at study entry, none of the 97 who received lowmolecular-weight heparin had new episodes of venous thromboembolism compared with 7 (6.8%) of 103 patients who received intravenous heparin (95% confidence interval for the difference, 1.9%-11.7%; P = .01). Major bleeding associated with initial therapy occurred in 1 patient (1.0%) w...

Low-molecular-weight heparin vs heparin in the treatment of patients with pulmonary embolism. American-Canadian Thrombosis Study Group.

BACKGROUND Pulmonary embolism (PE) occurs in 50% or more of patients with proximal deep-vein thrombosis. Low-molecular-weight heparin treatment is effective and safe in patients with deep vein thrombosis and may also be so in patients with PE. Recent rigorous clinical trials have established objective criteria for determining a high probability of PE by perfusion lung scanning. OBJECTIVE To c...

Low-molecular-weight Heparin in the Treatment of Acute Deep Vein Thrombosis and Pulmonary Embolism*

There are more than 170 000 hospital admissions each year for deep vein thrombosis (DVT) in the United States. Moreover, there are approximately 90 000 readmissions for recurrent venous thromboembolic events, with an average length of hospital stay between 5 days and 7 days. This article reviews the clinical evidence related to inpatient and outpatient treatment options and their efficacies in ...

Low Molecular Weight Heparin Overdose: A 10 Year Case Series

  Background: Low molecular weight heparin (LMWH) is used for the treatment and prevention of coagulative disorders. Few patients receiving therapeutic doses of LMWH develop major hemorrhage. Currently there are few reports in the literature on acute overdose on adults.  In this study, clinical profile, treatment and outcome of 21 patients who acutely overdosed enoxaparin are described. Method...

Low molecular weight heparin.