Low efficiency of β-alanine supplementation to increase muscle carnosine
نویسندگان
چکیده
منابع مشابه
Muscle carnosine metabolism and beta-alanine supplementation in relation to exercise and training.
Carnosine is a dipeptide with a high concentration in mammalian skeletal muscle. It is synthesized by carnosine synthase from the amino acids L-histidine and beta-alanine, of which the latter is the rate-limiting precursor, and degraded by carnosinase. Recent studies have shown that the chronic oral ingestion of beta-alanine can substantially elevate (up to 80%) the carnosine content of human s...
متن کاملRole of beta-alanine supplementation on muscle carnosine and exercise performance.
In this narrative review, we present and discuss the current knowledge available on carnosine and beta-alanine metabolism as well as the effects of beta-alanine supplementation on exercise performance. Intramuscular acidosis has been attributed to be one of the main causes of fatigue during intense exercise. Carnosine has been shown to play a significant role in muscle pH regulation. Carnosine ...
متن کاملMuscle carnosine loading by beta-alanine supplementation is more pronounced in trained vs. untrained muscles.
Carnosine occurs in high concentrations in human skeletal muscle and assists working capacity during high-intensity exercise. Chronic beta-alanine (BA) supplementation has consistently been shown to augment muscle carnosine concentration, but the effect of training on the carnosine loading efficiency is poorly understood. The aim of the present study was to compare muscle carnosine loading betw...
متن کاملExercise Training and Beta-Alanine-Induced Muscle Carnosine Loading
PURPOSE Beta-alanine (BA) supplementation has been shown to augment muscle carnosine concentration, thereby promoting high-intensity (HI) exercise performance. Trained muscles of athletes have a higher increase in carnosine concentration after BA supplementation compared to untrained muscles, but it remains to be determined whether this is due to an accumulation of acute exercise effects or to ...
متن کاملErgogenic Effects of β-Alanine and Carnosine: Proposed Future Research to Quantify Their Efficacy
β-alanine is an amino acid that, when combined with histidine, forms the dipeptide carnosine within skeletal muscle. Carnosine and β-alanine each have multiple purposes within the human body; this review focuses on their roles as ergogenic aids to exercise performance and suggests how to best quantify the former's merits as a buffer. Carnosine normally makes a small contribution to a cell's tot...
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ژورنال
عنوان ژورنال: Revista Brasileira de Educação Física e Esporte
سال: 2020
ISSN: 1981-4690,1807-5509
DOI: 10.11606/1807-5509202000030357