Low-Dose Non-Thermal Atmospheric Plasma Promotes the Proliferation and Migration of Human Normal Skin Cells

(1) Background: The purpose of this study was to investigate the effects low-dose non-thermal atmospheric plasma (NTP) on proliferation and migration human immortalized keratinocytes (HaCaT cells) its molecular mechanisms. (2) Methods: NTP HaCaT cells were detected by cell viability, wound healing assay, cycle, mitochondrial membrane potential detection, western blot, role reactive oxygen species (ROS) content in explored. (3) Results: Results showed that proportion G1-S phase transition, ability, expression Cyclin D1 STAT3 reached peak at 10 s treatment group, while viability PI3K, AKT, mTOR, ERK, WNT, β-catenin proteins 15 group. (4) Conclusions: These results manifested ROS produced promoted activating PI3K/AKT/mTOR signaling pathway also WNT/β-catenin pathway. Therefore, these will be useful for application healing.