Low-Cost Intradermal Rabies Vaccination Is Indeed Very Promising

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Low-cost intradermal rabies vaccination is indeed very promising.

TO THE EDITOR—We read with great interest the recent article by Wieten et al in Clinical Infectious Diseases [1] and, being involved in ongoing research strictly related to this topic, we wish to bring our contribution to their reflections. First, we fully agree that a lower-dose, abbreviated intradermal preand postexposure vaccination schedule may constitute a valid, shorter, and cheaper alter...

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TO THE EDITOR—We agree with Wieten and colleagues [1] that an abbreviated intradermal (ID) schedule would greatly reduce preexposure rabies vaccination cost, including for travelers [2, 3]. However, because lyophilized vaccines do not contain a preservative, once reconstituted, an ampoule must be kept in a refrigerator at <8°C and used within 8 hours. Therefore, for this approach to be costeffe...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2013

ISSN: 1058-4838,1537-6591

DOI: 10.1093/cid/cit080