Low Birth Weight, Cumulative Obesity Dose, and the Risk of Incident Type 2 Diabetes

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منابع مشابه

Low Birth Weight, Cumulative Obesity Dose, and the Risk of Incident Type 2 Diabetes

Background Obesity history may provide a better understanding of the contribution of obesity to T2DM risk. Methods 17,634 participants from the 1958 National Child Development Study were followed from birth to 50 years. Cumulative obesity dose, a measure of obesity history, was calculated by subtracting the upper cut-off of the normal BMI from the actual BMI at each follow-up and summing the ...

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Low Birth Weight and the Risk of Type II Diabetes

Background: In 1967 Barker first established the concept that a harmful intrauterine environment can have lifelong effects and contribute to adult onset disease. This Barker hypothesis, as it is now referred to, has since been cited in numerous disease associations including the well established correlation between low birth weight and adult onset type 2 diabetes. Studies have shown that full t...

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Birth weight and risk of type 2 diabetes, abdominal obesity and hypertension among Chinese adults.

OBJECTIVE To investigate the association between birth weight and risk of type 2 diabetes, abdominal obesity and hypertension among Chinese adults. RESEARCH METHODS AND PROCEDURES Nine hundred and seventy-three individuals from a population-based cross-sectional survey for the prevalence of type 2 diabetes conducted in Shanghai in 2002 were enrolled and followed up to 2004 with yearly examina...

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Common Variations in Perilipin rs1052700 and FTO rs3751812 Genes, Central Obesity, and Risk Type-2 Diabetes

Background: Perilipins are proteins at the external level of the lipid glob in adipocytes steroid-generating cells and play a central role in lipid storage and breakdown. FTO gene is associated with Type-2 diabetes (T2D) and increased fat mass. Association of Perilipin and FTO genes polymorphism with T2D was investigated. Methods: Clinical traits in a random sample of 183 Iranian men and wom...

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Dynapenic obesity and the risk of incident Type 2 diabetes: the English Longitudinal Study of Ageing.

AIM Obesity is a well-established risk factor for developing Type 2 diabetes. Evidence suggests that sarcopenia, the age-related decline in muscle mass and strength, may exacerbate diabetes risk in obese individuals. The aim of this study was to determine the combined effect of obesity and low muscle strength, dynapenia, on the risk of incident Type 2 diabetes in older adults. METHODS Partici...

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ژورنال

عنوان ژورنال: Journal of Diabetes Research

سال: 2018

ISSN: 2314-6745,2314-6753

DOI: 10.1155/2018/8435762