Loss of heterozygosity on chromosome 16 in sporadic Wilms' tumour
نویسندگان
چکیده
منابع مشابه
Loss of heterozygosity on chromosome 16q increases relapse risk in Wilms’ tumor: a meta-analysis
Wilms' tumor (WT) is the most frequent malignant renal tumor in children. The survival rate is lower in patients with recurrence, and the factors that influence relapse in WT are not fully understood. Loss of heterozygosity on chromosome 16q (LOH 16q) has been reported to be associated with the relapse in WT, but this remains controversial. We performed a meta-analysis to clarify this. PUBMED, ...
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PURPOSE Wilms' tumor is a childhood cancer of the kidney with an incidence of approximately 1 in 10,000. Cooccurrence of Wilms' tumor with 2q37 deletion syndrome, an uncommon constitutional chromosome abnormality, has been reported previously in three children. Given these are independently rare clinical entities, we hypothesized that 2q37 harbors a tumor suppressor gene important in Wilms' tum...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1998
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1998.651