Long Term Parathyroid Function Following Total Parathyroidectomy with Autotransplantation in Adult Patients with MEN2A

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Long term parathyroid function following total parathyroidectomy with autotransplantation in adult patients with MEN2A.

While there is no doubt that total thyroidectomy is necessary for medullary thyroid carcinoma (MTC) in multiple endocrine neoplasia type 2A (MEN2A) patients, there is still controversy regarding the management of the parathyroid glands. Although most, but not all, endocrine surgeons leave normal-appearing parathyroid glands in situ during thyroid surgery for MEN2A, we have employed total parath...

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Long-term results of subtotal vs total parathyroidectomy without autotransplantation in kidney transplant recipients.

HYPOTHESIS Total parathyroidectomy without autotransplantation in kidney transplant recipients leads to reduced recurrence rates and similar improvement of clinical symptoms compared with subtotal parathyroidectomy. DESIGN A retrospective cohort study. SETTING University clinic. PATIENTS Thirty-three patients with functioning renal grafts who underwent primary total (n = 17; group 1) or s...

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Total parathyroidectomy with autotransplantation in patients with renal hyperparathyroidism: indications and surgical approach.

OBJECTIVE renal hyperparathyroidism (rH) is one of the most serious complications in long-term hemodialysis patients. the purpose of this retrospective study was the evaluation of the surgical indications, parathyroid histology, and the results of total parathyroidectomy with autotransplantation (Ptx+At) in patients with rH. DESIGN the study included 36 patients with rH in whom Ptx+At was car...

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Total Parathyroidectomy with Presternal Intramuscular Autotransplantation in Renal Patients: A Prospective Study of 66 Patients

Surgical treatment of secondary (SHPT) and tertiary hyperparathyroidism (THPT) may involve various surgical approaches. The aim of this paper was to evaluate presternal intramuscular autotransplantation of parathyroid tissue as a surgical option in SHPT and THPT treatment. 66 patients with renal chronic disease underwent surgery from April 2000 to April 2005 at Universidade Federal São Paulo, B...

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Thyrotoxicosis Occurring in Secondary Hyperparathyroidism Patients Undergoing Dialysis after Total Parathyroidectomy with Autotransplantation

Secondary hyperparathyroidism (SHPT) is a common complication in chronic kidney disease (CKD) that is characterized by excessive synthesis of parathyroid hormone (PTH) and parathyroid hyperplasia.[1] The prevalence of CKD is estimated to be 5–10%, and the burden of CKD‐associated diseases is alarmingly high.[2,3] Despite advances in medical therapy for SHPT, surgical parathyroidectomy remains t...

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ژورنال

عنوان ژورنال: Endocrine Journal

سال: 2009

ISSN: 0918-8959,1348-4540

DOI: 10.1507/endocrj.k09e-005