Long-term cost-efficacy of rituximab in immune thrombocytopenic purpura
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چکیده
منابع مشابه
Long-term cost-efficacy of rituximab in immune thrombocytopenic purpura.
Correspondence Long-term cost-efficacy of rituximab in immune thrombocytopenic purpura Sir, Prior to 1981, the only effective treatments for increasing platelet count in immune thrombo-cytopenic purpura (ITP) were corticosteroids and splenectomy. More recently, intravenous immuno-globulin (IVIg) and Rh immunoglobulin (IV RhIg) have demonstrated efficacy. Other treatments, including danazol, aza...
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Background: Rituximab can induce a durable remission in plasma exchange refractory thrombotic thrombocytopenic purpura (TTP). Timing of Rituximab infusion in combination with plasma exchange (PE) and long term follow-up for probable side effects of such treatment is still lacking. Methods: This study was conducted among 10 patients with plasma exchange refractory TTP. According to the study de...
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Chronic immune thrombocytopenic purpura (ITP) is generally a more benign disease than previously thought. Currently it is recommended that only those patients with severe and/or symptomatic thrombocytopenia definitely require treatment. Additional factors, such as age, lifestyle, and uremia can also influence the hemorrhagic risk and should be carefully assessed before decision-making on the ap...
متن کاملAcute Immune Thrombocytopenic Purpura in Infants
Abstract Objective Immune thrombocytopenic purpura (ITP) manifests as an easy bruising or extravasation of blood from capillaries into skin and mucous membranes. The characteristics of acute ITP in infants have rarely been described. In order to better understand acute ITP in infants, the characteristics of the disease at this age group was investigated. Material and Methods The present des...
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BACKGROUND AND OBJECTIVES Immune thrombocytopenic purpura (ITP) is an acquired autoimmune disease characterized by platelet destruction. Glucocorticoids are the first-choice treatment, resulting in a complete (CR) or partial (PR) response in 70-80% of cases. In most cases, however, response is transient or glucocorticoid-dependent. For these and for selected patients with acute refractory ITP, ...
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ژورنال
عنوان ژورنال: QJM: An International Journal of Medicine
سال: 2005
ISSN: 1460-2393,1460-2725
DOI: 10.1093/qjmed/hci130