Long Non-Coding RNA Taurine Upregulated Gene 1 Affects Cell Apoptosis and Cell Cycle through Downregulating Cell Division Control Protein 42 Homolog in Osteoblasts

To explore the regulation and potential mechanism of long non-coding ribonucleic acid taurine upregulated gene 1 on apoptosis cell cycle osteoblasts is main purpose. The overexpression plasmid small interfering were used to regulate expression in osteoblasts. was detected by quantitative reverse transcription polymerase chain reaction effect flow cytometry, western blot analyses detect division control protein 42 homolog combined with functional recovery experiments verify that regulated through homolog. Silencing promoted blocked from entering growth 2 phase/mitotic phase. Overexpression had no significant inhibited In addition, compared group, overexpression+cell antagonist group increased significantly. Compared silencing silencing+cell agonist significantly reduced number phase increased. promotes prevented downregulating normal level maintains stabilizing