Lola Hoffmann: Terapeuta Jungiana (1904-1988)

Gernot Hoffmann

Lola regulates midline crossing

In each hemisegment of the developing Drosophila ventral nerve cord, the axons of ~20% of the 350 or so embryonic interneurons grow longitudinally on the same side of the midline where their cell bodies lie; they never cross the midline of the CNS (Schmid et al., 1999). In part, this pattern of axon growth reflects the existence of molecular forces that repel axons away from the midline (Klambt...

LoLA wird Pfadfinder

LoLA ist ein erreichbarkeitsgraphbasiertes Werkzeug f ur Stellen/Transitions{Netze. Hier geht es um LoLAs Fahigkeit, erreichbare Zustande mit vorgegebenen Eigenschaften zu suchen und im Erfolgsfall einen solchen Zustand mit einem Weg von der Anfangsmarkierung dorthin anzugeben. Die Besonderheit besteht darin, da wahrend der Suche nur zwei Zustande gespeichert werden: der Anfangszustand und...

Dmd065755 1891..1904

The cytochrome P450 2C19 (CYP2C19) enzyme plays an important role in the metabolism of many commonly used drugs. Relatively little is known about CYP2C19 inhibitors, including compounds of natural origin, which could inhibit CYP2C19, potentially causing clinically relevant metabolism-based drug interactions. We evaluated a series (N = 49) of structurally related plant isoquinoline alkaloids for...

Op-scan130187 1904..1913

Silvio Ionta,* Roberto Martuzzi, Roy Salomon, and Olaf Blanke Center for Neuroprosthetics, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland; Laboratory of Cognitive Neuroscience, Brain-Mind Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland; and Department of Neurology, University Ho...