Locoregional Therapy for Intrahepatic Cholangiocarcinoma: The Role of Intra-Arterial Therapies

Intrahepatic cholangiocarcinoma (ICC) is a rare disease with rising incidence. While surgical resection the only curative option, process often identified in advanced stages, as this malignancy remains clinically silent early development. Only one-third of patients are eligible for at time diagnosis. For who cannot undergo resection, intra-arterial therapies reasonable palliative treatment options; occasions, these may be bridging therapies, well. The premise bland embolization and most chemoembolization that arterial supply tumor occluded to induce necrosis, while radioembolization utilizes flow deliver radiation therapy. In review, we discuss use transarterial embolization, chemoembolization, selective internal therapy ICC. Phase III randomized controlled clinical trials difficult tailor extremely aggressive disease, but ultimately, further investigation should pursued define patient population will derive greatest benefit from each modality.