Locally advanced esophageal cancer: What becomes of 5-year survivors?

Locally Advanced Esophageal Cancer

Preoperative therapy in locally advanced esophageal cancer

Esophageal cancer is an aggressive malignancy associated with dismal treatment outcomes. Presence of two distinct histopathological types distinguishes it from other gastrointestinal tract malignancies. Surgery is the cornerstone of treatment in locally advanced esophageal cancer (T2 or greater or node positive); however, a high rate of disease recurrence (systemic and loco-regional) and poor s...

Educational Conference Management of Locally Advanced Esophageal Cancer

Introduction The estimated incidence of esophageal cancer in the United States is about 16,640 new cases for 2010 with a male to female ratio of 5:1. At diagnosis, about 50% of patients have metastatic disease, and only 60% of patients with locoregional disease can undergo a curative resection. Of those, nearly 70% have disease in the lymph nodes. For all stages, the 5-year overall survival is ...

Change in employment status of 5-year cancer survivors.

AIMS To follow the employment status of 5-year cancer survivors for 5 years after diagnosis with their first lifetime invasive cancer and to identify socio-demographic, work-related and cancer-related predictors of employment status after 5 years. METHODS This prospective registry study concerned all 3278 people in Norway (18-61 years old) diagnosed with their first lifetime invasive cancer i...

Risk Factors for Esophageal Fistula Associated With Chemoradiotherapy for Locally Advanced Unresectable Esophageal Cancer

Esophageal fistula is a critical adverse event in patients treated with chemoradiotherapy (CRT) for locally advanced esophageal cancer. However, risk factors associated with esophageal fistula formation in patients receiving CRT have not yet been elucidated.We retrospectively analyzed data obtained from 140 patients who were enrolled in a phase II/III trial comparing low-dose cisplatin with sta...