Localized Scleroderma: Predisposing and Triggering Factors

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Localized Scleroderma: Predisposing and Triggering Factors

The etiology of localized scleroderma remains unclear. The objective of this article is to review different theories of etiology, specifically provocative and predisposing factors for the development of localized scleroderma. The mini-review presents the factors, which may influence the occurrence of localized scleroderma. The genetic predisposition for the development of scleroderma is a relev...

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Morphea (localized scleroderma) is an autoimmune disease characterized by sclerosis of the skin and, in some cases, subcutaneous tissue. It occurs in children and adults. It is distinct from systemic sclerosis, but may nevertheless be associated with significant functional and cosmetic impairment. Morphea has several distinct subtypes, including circumscribed, linear, and generalized, all of wh...

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ژورنال

عنوان ژورنال: The Open Dermatology Journal

سال: 2017

ISSN: 1874-3722

DOI: 10.2174/1874372201711010001