Localization of blood proteins thrombospondin1 and ADAMTS13 to cerebral corpora amylacea
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چکیده
منابع مشابه
Localization of blood proteins thrombospondin1 and ADAMTS13 to cerebral corpora amylacea.
Corpora amylacea (CA) have long been described in aging brains and in patients with neurodegenerative conditions, but their origins have been debated. It has been proposed that CA represent collections of nervous system breakdown products that accumulate within astrocytic cytoplasm. In support of this, studies have shown that CA include glycosylated material, ubiquitin, and an assortment of pro...
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AIM To determine the presence and nature of amyloid in prostatic corpora amylacea using immunohistological studies. METHODS Prostatic tissue from 18 transurethral and two open resection specimens was studied. Paraffin wax embedded tissue sections were stained with haematoxylin and eosin and the alkaline Congo red method with and without previous treatment with potassium permanganate. Sections...
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UNLABELLED Hippocampal sclerosis (HS) is the commonest pathology in epileptic patients undergoing temporal lobe epilepsy surgery. Beside, there are an increased density of corpora amylacea (CA) founded in 6 to 63% of those cases. OBJECTIVE verify the presence of CA and the clinical correlates of their occurrence in a consecutive series of patients undergoing temporal surgery with diagnosis of...
متن کاملSpinal corpora amylacea and motor neuron disease: a quantitative study.
OBJECTIVE To test the hypothesis that as there is growing evidence that corpora amylacea, or amyloid bodies, in the CNS are derived primarily from neurons, it might be expected that their numbers in the spinal cord would decline with loss of neurons in motor neuron degeneration as they do in the retina on destruction of ganglion cells by glaucoma. METHODS The numbers of corpora amylacea were ...
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The presence of corpora amylacea (CA) in the CNS is associated with both normal aging and neurodegenerative conditions including Alzheimer's disease (AD) and vascular dementia (VaD). CA are spherical bodies ranging in diameter (10-50 μm) and whose origin has been documented to be derived from both neural and glial sources. CA are reported to be primarily composed of glucose polymers, but approx...
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ژورنال
عنوان ژورنال: Neuropathology
سال: 2009
ISSN: 0919-6544,1440-1789
DOI: 10.1111/j.1440-1789.2009.01024.x