Local Radiation Therapy for Palliation in Patients With Multiple Myeloma of the Spine

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Local radiotherapy for palliation in multiple myeloma patients with symptomatic bone lesions.

PURPOSE To evaluate the clinical outcomes of symptomatic bone lesions in patients with multiple myeloma (MM) who received local radiotherapy (LRT). MATERIALS AND METHODS Fifty-one patients with 87 symptomatic bone lesions treated via LRT were analyzed. LRT was delivered at a median total dose of 21 Gy (range, 12 to 40 Gy) in a median of 7 fractions (range, 4 to 20 fractions). The clinical out...

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Current Role of Radiation Therapy for Multiple Myeloma

BACKGROUND Radiation therapy (RT) is a treatment modality traditionally used in patients with multiple myeloma (MM), but little is known regarding the role and effectiveness of RT in the era of novel agents, i.e., immunomodulatory drugs and proteasome inhibitors. METHODS We retrospectively reviewed data from 449 consecutive MM patients seen at our institute in 2010-2012 to assess indications ...

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ژورنال

عنوان ژورنال: Frontiers in Oncology

سال: 2019

ISSN: 2234-943X

DOI: 10.3389/fonc.2019.00601