Local membrane deformation and micro-injury lead to qualitatively different responses in osteoblasts

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Local membrane deformation and micro-injury lead to qualitatively different responses in osteoblasts

Micro-damage of bone tissue is known to regulate bone turnover. However, it is unknown if individual bone cells can differentiate between membrane deformation and micro-injury. We generated osteoblasts from mouse bone marrow or bone morphogenetic protein 2-transfected C2C12 cells. Single cells were mechanically stimulated by indentation with the atomic force microscopy probe with variable force...

متن کامل

Qualitatively different memory states in Lymnaea as shown by differential responses to propranolol.

Mixed results with the synthetic β-adrenergic receptor blocker, propranolol, have been reported in human populations with regards to its therapeutic efficacy for PTSD treatments targeting the memory reconsolidation process. Stress alters the ability to form and maintain memory, but whether the causal neuronal mechanisms underling memory formation in PTSD are similar to normal memory is not clea...

متن کامل

Local and general responses to injury in the newborn rabbit.

Some physiological responses to experimental bilateral hind limb ischaemia have been studied and compared in neonatal and young rabbits. The fluid loss into the injured limbs after removal of the tourniquets has been expressed as a percentage of the plasma volume and of the total body water at the different ages. The reactivity of skin blood vessels to a variety of known mediators of an inflamm...

متن کامل

Two different KIT mutations may lead to different responses to imatinib in metastatic gastrointestinal stromal tumor

Copyright © 2018 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. pISSN 1226-3303 eISSN 2005-664...

متن کامل

Detecting qualitatively different behaviours in complex models

We suggest that one of the main purposes of modelling is to explore the potential dynamical behaviours a system can display. Within this view, we aim to discriminate model behaviours which appear to be qualitatively different given a problem at hand. This approach fits nicely within a pre-cautionary approach to ecological and social problems aimed to inform policy-makers on the range of scenari...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: F1000Research

سال: 2014

ISSN: 2046-1402

DOI: 10.12688/f1000research.4448.1