منابع مشابه
Local innervation and atrial fibrillation.
A trial fibrillation (AF) is the most common human arrhythmia in the world and, depending on individual demographics, afflicts from 0.1% to 4% of the general population. 1 With the steady rise of cardiovascular disease in the industrialized world, it is no surprise that the incidence of AF is also increasing. 2,3 However, despite its ubiquitous presence in adult medicine, AF remains an enigmati...
متن کاملAutonomic innervation, atrial electrogram morphology, and atrial fibrillation.
everal lines of evidence suggest that autonomic innervation lays a role in the generation of atrial fibrillation (AF). anglionated plexi (GPs) that modulate autonomic inneration have been identified over both atria, particularly the ulmonary vein (PV) antral regions. Stimulation of GPs esults in the local release of parasympathetic and sympahetic neurotransmitters, which may lead to increased a...
متن کاملAtrial fibrillation produced by prolonged rapid atrial pacing is associated with heterogeneous changes in atrial sympathetic innervation.
BACKGROUND Structural and electrophysiological changes of the atria occur with prolonged rapid rates; however, the effects of sustained atrial fibrillation (AF) on autonomic innervation of the atria are unknown. We hypothesized that electrophysiological remodeling from rapid atrial rates is accompanied by altered atrial autonomic innervation. METHODS AND RESULTS Six dogs (paced group) underwe...
متن کاملAtrial function and atrial fibrillation
s $7 295 Decreased fractional area change of left atrial appendage contributes to development of persistent atrial fibrillation in patients of lone paroxysmal atrial f ibr i l lat ion E.-J. Cho, H.-J. Youn, T.-H. Rho, H.-K. Jeon, H.-O. Jung, C.-J. Kim, J.-H. Kim, S.-J. Hong. Catholic University of Korea, Internal medicine, College of Medicine, Seoul, Korea, Republic of Background and Purpose: A...
متن کاملSynaptic Plasticity in Cardiac Innervation and Its Potential Role in Atrial Fibrillation
Synaptic plasticity is defined as the ability of synapses to change their strength of transmission. Plasticity of synaptic connections in the brain is a major focus of neuroscience research, as it is the primary mechanism underpinning learning and memory. Beyond the brain however, plasticity in peripheral neurons is less well understood, particularly in the neurons innervating the heart. The at...
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ژورنال
عنوان ژورنال: Circulation
سال: 2013
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.113.001596