Local application of biphosphonate as a biochemical barrier against bone graft resorption in mandibular reconstructio

Local treatment of a bone graft by soaking in zoledronic acid inhibits bone resorption and bone formation. A bone chamber study in rats

BACKGROUND Bone grafts are frequently used in orthopaedic surgery. Graft remodelling is advantageous but can occur too quickly, and premature bone resorption might lead to decreased mechanical integrity of the graft. Bisphosphonates delay osteoclastic bone resorption but may also impair formation of new bone. We hypothesize that these effects are dose dependent. In the present study we evaluate...

Demineralized Bone Matrix, as a Graft Enhancer of Auto-Local Bone in Posterior Lumbar Interbody Fusion

STUDY DESIGN A case controlled study with prospective data collection. PURPOSE To evaluate the early influence and the final consequence of demineralized bone matrix (DBM) on auto-local bone as a graft enhancer in posterior lumbar interbody fusion (PLIF). OVERVIEW OF LITERATURE DBM is known as an osteoinductive material; however, it has not been clearly recognized to enhance auto-local bone...

Resorption of Autogenous Bone Graft in Cranioplasty: Resorption and Reintegration Failure

OBJECTIVE Re-implantation of autologous skull bone has been known to be difficult because of its propensity for resorption. Moreover, the structural characteristics of the area of the defect cannot tolerate physiologic loading, which is an important factor for graft healing. This paper describes our experiences and results with cranioplasty following decompressive craniectomy using autologous b...

The effect of local delivery of Iron Chelators on Bone Regeneration and Osteoclast Mediated Bioceramic Bone Graft Resorption

Mandibular tori as a source for onlay bone graft augmentation: a surgical procedure.

Conventional dentistry has provided acceptable treatment alternatives for the partially or fully edentulous patient for decades. Recent innovations have provided clinicians with an assortment of new techniques to restore the function of these patients. Established treatment alternatives have been significantly enhanced, resulting in increased acceptance of predictable dental implant restoration...