LncRNA HCP5 Induces Gastric Cancer Cell Proliferation, Invasion, and EMT Processes Through the miR-186-5p/WNT5A Axis Under Hypoxia
نویسندگان
چکیده
منابع مشابه
The miR-383-LDHA axis regulates cell proliferation, invasion and glycolysis in hepatocellular cancer
Objective(s): To explore the correlation between expression patterns and functions of miR-383 and LDHA in hepatocellular cancer (HCC). Materials and Methods: We detected the expression of miR-383 and LDHA in 30 HCC tissues and their matched adjacent normal tissues using qRT-PCR. Then we performed MTT assay, foci formation assay, transwell migration assay, glucose uptake assay and lactate produc...
متن کاملMiR-493 suppresses the proliferation and invasion of gastric cancer cells by targeting RhoC
Objective(s):MiRNAs have been proposed to be key regulators of tumorigenesis, progression and metastasis. However, their effect and prognostic value in gastric cancer is still poorly known. Materials and Methods: Gastric cancer cell lines were cultured. Tissue samples obtained from 36 gastric cancer patients were used for quantitative real-time PCR (qRT-PCR) analysis. The tissue microarrays (T...
متن کاملthe mir-383-ldha axis regulates cell proliferation, invasion and glycolysis in hepatocellular cancer
objective(s): to explore the correlation between expression patterns and functions of mir-383 and ldha in hepatocellular cancer (hcc). materials and methods: we detected the expression of mir-383 and ldha in 30 hcc tissues and their matched adjacent normal tissues using qrt-pcr. then we performed mtt assay, foci formation assay, transwell migration assay, glucose uptake assay and lactate produc...
متن کاملLncRNA-TUG1/EZH2 axis promotes cell proliferation, migration and the EMT phenotype formation through sponging miR-382
Pancreatic carcinoma (PC) is the one of the most common and malignant cancer in the world. Despite many effort have been made in recent years, the survival rate of PC still remains unsatisfied. Therefore, investigating the mechanisms underlying the progression of PC might facilitate the development of novel treatments that improve patient prognosis. LncRNA Taurine Up–regulated Gene 1 (TUG1) was...
متن کاملmiR-186 affects the proliferation, invasion and migration of human gastric cancer by inhibition of Twist1
Recent evidence shows that miRNAs are dysregulated in a variety of cancers including gastric cancer (GC), and emerging as key oncogenes or tumor suppressors. In this study, qRT-PCR was used to analyze the expression of miR-186 in GC tissues and adjacent non-cancerous tissues, and then more in-vitro experiments were used to investigate the role of miR-186 in GC cells. Here, we identified miR-186...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Cell and Developmental Biology
سال: 2021
ISSN: 2296-634X
DOI: 10.3389/fcell.2021.663654