LK or IGF1R: When selectivity hurts
نویسندگان
چکیده
منابع مشابه
LK or IGF1R: When selectivity hurts
success of small molecule tyrosine kinase (TKI) inhibitors in cancer treatment and recent studies both in vitro and in vivo sparked interest in targeting the insulin-like growth factor receptor 1 (IGF1R). The development of several antibodies as well as small molecule inhibitors aimed at this receptor continues to be the subject of numerous preclinical studies and clinical trials. IGF1R, a tyro...
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License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be f...
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ژورنال
عنوان ژورنال: Aging
سال: 2015
ISSN: 1945-4589
DOI: 10.18632/aging.100753