LİYAKAT TEMELLİ BÜROKRASİ: KORE KAMU SINAVLARI (GWAGEO) (958-1894) - THE MERIT-BASED BUREAUCRACY: THE CIVIL SERVICE EXAMINATION (GWAGEO) IN KOREA (958-1894)
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چکیده
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Carbamazepine (CBZ) is widely used as an antiepileptic agent and causes rare but severe liver injury in humans. It has been generally recognized that reactive metabolites formed via the metabolic activation reaction contribute to the onset of liver injuries by several drugs. However, the role of CBZ metabolism in the development of liver injury is not fully understood. In this study, we develop...
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Complexins constitute a family of four synaptic high-affinity SNARE complex–binding proteins. They positively regulate a late, post-priming step in Ca2+-triggered synchronous neurotransmitter release, but the underlying molecular mechanisms are unclear. We show here that SNARE complex binding of complexin I (CplxI) via its central a-helix is necessary but, unexpectedly, not sufficient for its k...
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64/2 1964a). Within several days after hypophysectomy, this gland atrophies and the proportion of plasmatic cortisol diminishes: this proportion drops from 4.6 / g per 100 ml in the intact animal po less than 1 .)1g 7 days after hypophysectomy, however, a single injection of mammalian ACTH in the hypophysectomized animal, kept at 16° C., will bring about a return to normal glandular weight with...
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Ribonucleoprotein particles are central to numerous cellular pathways, but their study in vitro is often complicated by heterogeneity and aggregation. We describe a new technique to characterize these complexes trapped as homogeneous species in a nondenaturing gel. Using this technique, in conjunction with phosphorothioate footprinting analysis, we identify the proteinbinding site and RNA foldi...
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In this report, we show the theoretical results of the formation spectra of the η′-nucleus systems in the (p, d) reactions based on the latest theoretical considerations of the η′ properties in nucleus. The results shown here are important to give predictions and supports to the future experiment, and to make clear relations between the η′ mesic nucleus formation spectra and the modifications o...
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ژورنال
عنوان ژورنال: Mehmet Akif Ersoy Üniversitesi Sosyal Bilimler Enstitüsü Dergisi
سال: 2018
ISSN: 1309-1387
DOI: 10.20875/makusobed.413841