Liver function tests: defining what's normal

Effect of Ramadan Fast on Liver Function Tests

Abnormal Liver Function Tests

LFTs are not specific to specific systems or disease processes, yet abnormalities may indicate significant or serious disease. Interpreting abnormal LFTs and trying to diagnose any underlying liver disease is a common scenario in Primary Care. Single abnormalities in LFTs are difficult to localise and diagnose [2] . However, the pattern of abnormalities tests helps determine origin of the issue...

Liver Function Tests

The liver may be regarded as a system of branching bile ducts which terminate in numerous blind tubules, the bile canaliculi. The walls are formed by the liver cells, which are externally in contact with the capillaries of the portal venous system and the hepatic arterial system: these cells are homogeneous and show no obvious signs of differentiation or specialization. But in spite of its anat...

Abnormal Liver Function Tests:

Serum levels of aspartate aminotransferase and alanine aminotransferase that exceed 1000 IU/L indicate acute viral hepatitis (A, B and, rarely, C), acute drug toxicity (eg, acetaminophen overdose or isoniazid hepatotoxicity), or ischemic liver injury. In chronic hepatitis (ie, hepatitis B or C or autoimmune), values range from mildly elevated to usually less than 400 IU/L. Elevated levels of al...

Liver histology and follow up of 68 patients with ulcerative colitis and normal liver function tests.

Hepatobiliary disorders are well known complications in patients with ulcerative colitis but it is not possible to predict those patients with ulcerative colitis who will eventually develop liver disease. In this study, liver biopsies from 74 patients with ulcerative colitis have been reevaluated. None of the patients showed clinical or biochemical signs of liver disease at the time of biopsy. ...