Little Things Mean a Lot

Spending a little to save a lot

Phase III studies of disease-modifying agents for neurodegenerative disorders generally require hun­ dreds of patients to be followed for at least 2 years at a cost of millions of dollars. No matter how promis­ ing an agent may appear in preclinical studies and animal models, preliminary evidence that the treat­ ment is likely to be helpful in patients (proof-of­ concept) and that it is reasona...

Give a little ... get a lot.

From little things big things grow: . . .

Little things make a big difference.

What do you do to start reading little things make a big difference? Searching the book that you love to read first or find an interesting book that will make you want to read? Everybody has difference with their reason of reading a book. Actuary, reading habit must be from earlier. Many people may be love to read, but not a book. It's not fault. Someone will be bored to open the thick book wit...

A Variance Explanation Paradox: When a Little is a Lot

Concerning a single major league at bat, the percentage of variance in batting performance attributable to skill differentials among major league baseball players can be calculated statistically. The statistically appropriate calculation is seriously discrepant with intuitions about the influence of skill in batting performance. This paradoxical discrepancy is discussed in terms of habits of th...