منابع مشابه
Lithium nephrotoxicity
After nearly two decades of concern and controversy surrounding the long-term effects of lithium on the kidney, the fact that lithium is capable of causing a major disturbance in water balance, manifest as polyuria and secondary polydipsia, remains undisputed. A decreased urinary concentrating ability (nephrogenic diabetes insipidus) with a disturbed responsiveness of the distal nephron to the ...
متن کاملLithium nephrotoxicity.
Lithium has been widely used in the treatment of bipolar disorder. Its renal toxicity includes impaired urinary concentrating ability and natriuresis, renal tubular acidosis, tubulointerstitial nephritis progressing to chronic kidney disease and hypercalcemia. The most common adverse effect is nephrogenic diabetes insipidus, which affects 20-40% of patients within weeks of lithium initiation. C...
متن کاملLithium nephrotoxicity: a review.
Lithium, a group I alkali metal, is widely used for treatment of manic-depressive psychosis. A number of toxic side effects have been reported, among which the most common ones are nephrogenic diabetes insipidus, distal tubular acidosis, and impairment of renal concentrating ability. The proposed mechanisms in the literature of these renal complications of lithium salt therapy are reviewed. Non...
متن کاملLithium Nephrotoxicity: When Is the Time for Nephrology Consultation?
1. Dept. of Nephrology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran 2. Dept. of Clinical Pharmacy, School of Pharmacy-International Campus, FCRDC, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran 3. Dept. of Nephrology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran 4. Dept. of Radiology, Shahid Beheshti University of Medical...
متن کامل[An investigation of cyclosporine A (CyA) nephrotoxicity by lithium clearance].
It has been widely recognized that cyclosporine A (CyA) is useful in transplantation of the kidneys. On the other hand, the nephrotoxicity as one of its adverse effects is clinically important. There have been accumulated pieces of pathological evidence that CyA causes the renal proximal tubule damage. However, there are few reports available on the changes in the proximal tubular function. Rec...
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ژورنال
عنوان ژورنال: International Journal of Bipolar Disorders
سال: 2015
ISSN: 2194-7511
DOI: 10.1186/s40345-015-0028-y