Listeria exploits damage and death to spread bad news

Listeria monocytogenes Exploits Normal Host Cell Processes to Spread from Cell to Cell✪

The bacterial pathogen, Listeria monocytogenes, grows in the cytoplasm of host cells and spreads intercellularly using a form of actin-based motility mediated by the bacterial protein ActA. Tightly adherent monolayers of MDCK cells that constitutively express GFP-actin were infected with L. monocytogenes, and intercellular spread of bacteria was observed by video microscopy. The probability of ...

hiv/aids good news and bad news

Delivering bad news to patients.

When physicians lack proper training, breaking bad news can lead to negative consequences for patients, families, and physicians. A questionnaire was used to determine whether a didactic program on delivering bad news was needed at our institution. Results revealed that 91% of respondents perceived delivering bad news as a very important skill, but only 40% felt they had the training to effecti...

The Good News and the Bad News

There is much that is attractive about Michael Burawoy’s examination of the critical turn to a public sociology. I find plausible his account of the academic nature of 1970s radical sociology especially that mobilized notions such as Althusser’s “theoretical practice.” I also was cheered to read the account of the positive developments currently in train in the USA and especially with how socia...

Consistent Good News and Inconsistent Bad News

Good news is more persuasive when it is more consistent, and bad news is less damaging when it is less consistent. We show when Bayesian updating supports this intuition so that a biased sender prefers more or less variance in the news depending on whether the mean of the news exceeds expectations, and we apply the result to selective news distortion by a manager of multiple projects. If news f...