Liquid Biopsy-Based Biomarkers of Treatment Response and Resistance
نویسندگان
چکیده
منابع مشابه
Liquid Biopsy of Hepatocellular Carcinoma: Circulating Tumor-Derived Biomarkers
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide due to latent liver disease, late diagnosis, and nonresponse to systemic treatments. Till now, surgical and/or biopsy specimens are still generally used as a gold standard by the clinicians for clinical decision-making. However, apart from their invasive characteristics, tumor biopsy only mirrors a sing...
متن کاملLiquid biopsy and therapeutic response: Circulating tumor cell cultures for evaluation of anticancer treatment
The lack of a robust anticancer drug screening system to monitor patients during treatment delays realization of personalized treatment. We demonstrate an efficient approach to evaluate drug response using patient-derived circulating tumor cell (CTC) cultures obtained from liquid biopsy. Custom microfabricated tapered microwells were integrated with microfluidics to allow robust formation of CT...
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ژورنال
عنوان ژورنال: Cancer Cell
سال: 2020
ISSN: 1535-6108
DOI: 10.1016/j.ccell.2020.03.012