Liposomes as vehicles for topical ophthalmic drug delivery and ocular surface protection

Introduction: The development of ophthalmic formulations able to deliver hydrophilic and hydrophobic drugs the inner structures eye restore preocular tear film has been a leading topic discussion over last few years. In this sense, liposomes represent suitable strategy achieve these objectives in ocular drug delivery.Areas covered: Knowledge different physiological anatomical structures, specially surface are critical better understanding comprehending characteristics required for topical liposomal formulations. review, several features discussed such as main materials used their fabrication, basic structure preparation methods, from already established novel techniques, allowing control design special characteristics. Besides, physicochemical properties, purification processes strategies overcome delivery or encapsulation challenges also presented. Expert opinion: Regarding liposomes, there some that can be redesigned. Specific biocompatible biodegradable presenting therapeutic lipidic compounds polymers significantly change way tackling diseases. entail an effective, safe versatile treatment diseases clinical practice.