Lipoprotein traffic control

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Proteins of the p120 family have been implicated in the regulation of cadherin-based cell adhesion, but their relative importance in this process and their mechanism of action have remained less clear. Three papers in this issue suggest that p120 plays a key role in maintaining normal levels of cadherin in mammalian cells, and that it may do so by regulating cadherin trafficking (Chen et al., 2...

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ژورنال

عنوان ژورنال: Nature Medicine

سال: 2012

ISSN: 1078-8956,1546-170X

DOI: 10.1038/nm.2785