منابع مشابه
Lipoprotein autoantibodies: measurement and significance.
Two decades ago, well before the inflammatory nature of arteriosclerosis was generally accepted, several groups reported the finding of immunoglobulins and various complement components in atheromatous plaques of humans and rabbits (12, 42, 69). A decade later apolipoprotein B (ApoB) extracted from atheromatous lesions was found to react with monoclonal antibodies against malondialdehyde (MDA)a...
متن کاملautoantibodies against modified low density lipoprotein in patients with coronary heart disease and normal individuals
different classes of autoantibodies against two antigenic forms of modified low density lipoprotein (mod-ldl) were detected in 140 patients by indirect elisa method. investigated autoantibodes included total immunoglobulins (igt). immunoglobulin g (igg), and immunoglobulin m (igm) against oxidized ldl with copper ions (ox-ldl) and modified ldl with malondialdehyde (mal-ldl) (igt-o) igt against ...
متن کاملAutoantibodies Against Modified Low Density Lipoprotein Noniipid Factor of Blood Plasma That Stimulates Foam Cell Formation
The blood serum of patients with coronary atherosclerosis possesses an ability to induce the accumulation of cellular lipids in primary cultures of human aortic intimal cells. Factors responsible for this property of the atherosclerotic patients' sera are represented by modified (desialylated) low density lipoprotein (LDL) and a noniipid factor interacting with LDL. It was assumed that the noni...
متن کاملAutoantibodies against oxidized low-density lipoprotein and cardiolipin in patients with coronary heart disease.
Autoantibodies against oxidized low density lipoprotein (oxLDL) have been proposed to be independent predictors of atherosclerotic vascular disease. Because the levels of autoantibodies against oxLDL and cardiolipin might be modified by the presentation and severity of coronary heart disease (CHD), we measured their levels in patients with different manifestations of CHD (n=415, mean age 61 yea...
متن کاملAutoantibodies against modified low density lipoprotein. Nonlipid factor of blood plasma that stimulates foam cell formation.
The blood serum of patients with coronary atherosclerosis possesses an ability to induce the accumulation of cellular lipids in primary cultures of human aortic intimal cells. Factors responsible for this property of the atherosclerotic patients' sera are represented by modified (desialylated) low density lipoprotein (LDL) and a nonlipid factor interacting with LDL. It was assumed that the nonl...
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ژورنال
عنوان ژورنال: Clinical and Vaccine Immunology
سال: 2003
ISSN: 1556-6811,1556-679X
DOI: 10.1128/cdli.10.4.499-505.2003