Lipid Synthesis in Cutaneous Xanthoma

Lipid Studies in Xanthoma

Successful Treatment of Xanthoma Disseminatum with Combined Lipid Lowering Agents

Received October 18, 2011, Revised November 29, 2011, Accepted for publication November 30, 2011 Corresponding author: Moon-Bum Kim, M.D., Ph.D., Department of Dermatology, Pusan National University Hospital, Pusan National University School of Medicine, 179 Gudeok-ro, Seo-gu, Busan, 602-739, Korea. Tel: 82-51-240-7338, Fax: 82-51-245-9467, E-mail: [email protected] This is an Open Access artic...

Cholesterol synthesis and esterification in experimental xanthoma tissues.

We studied cholesterol metabolism in experimental xanthoma tissues which were induced by injection of high molecular weight sodium dextran sulfate into the dermis of hypercholesterolemic rabbits. Control studies were performed on dermal specimens of the dextran sulfate-injected site of normolipemic rabbits. Cholesterol accumulation was much greater in the hypercholesterolemic rabbit tissues tha...

Cutaneous xanthoma in association with paraproteinemia in the absence of hyperlipidemia.

In the present report we describe a patient with multiple myeloma and long-standing paraproteinemia who developed xanthoma in the absence of an elevation in plasma cholesterol or triglyceride concentrations. Studies demonstrated that our patient's monoclonal IgG antibody interacted with apoprotein B-100. The LDL-antibody complex isolated from our patient did not affect the degradation of LDL by...

Eruptive xanthoma.

History A two-month-old girl with unremarkable birth history presented with sudden onset of erythematous papules on the limbs and face for one week. There was no systemic upset, and she remained asymptomatic. Her sister had a history of hypertriglyceridaemia under treatment. The patient's other family members enjoyed good physical health and there was no family history of premature coronary hea...