Lipid profile of obese children with metabolic syndrome

Relevance. Disorders of lipid metabolism are closely related to abdominal (visceral) obesity and MS in adolescence, as well the development early cardiovascular complications adulthood. The purpose study: Study features blood spectrum obese children, depending on presence signs MS. Materials methods: 483 children (SDS BMI ≥ 2.0) (349 boys 234 girls) aged from 5 16 years were. I group — 237 (145 92 with (IDF, 2007), II 246 (140 106 without examination included anamnesis collection, anthropometry, PRESSURE measurement, ultrasound organs, biochemical serum profile. Results. Change profile were detected 76.8% 43.9% have 38,0% changes a single metric, 35.6% two, 3.0% three more indicators, whereas most frequently recorded only one (36,2%), at least two indicators (7,7%). In there was significant increase TG, atherogenicity coefficient, decrease HDL cholesterol. 53.6% 8.5% had an level 52.8% 24.0% levels, respectively. combination hypertriglyceridemia hypo-α-lipoproteidemia diagnosed exclusively (27.0%), which –62.5%, girls –31.5%. frequency hyperglyceridemia hypo-α-lipoproteinemia regardless age significantly higher than group, while both groups compared Hypo-α-lipoproteinemia. under 10 also disorders-hypo-α-lipoproteidemia 27.8%, hypertriglyceridemia‑11,1%. An TG NAFLD not often it, but comparison group. 46,5% 58.4% it cholesterol; these values 15.7% 17.6%, Hypo-α-lipoproteidemia observed 28.9% 22,5% it; they registered separately. Regardless 48,7% who for 1–2 60,1% disease duration or disorders. Violations component 31,6% 31.1% respectively, violations components increased 17.1% 29.0%. Conclusions. half MS, disorders form (53.6%) (52.8%), is uncomplicated (8.5% 24.0%). Exclusively (27%). 28% age, detected, 11% hypertriglyceridemia, indicates that dyslipidemia formed them young progresses disease, its manifestation violation excretion tissue cholesterol due levels. prognostically unfavorable risk factor formation progression pronounced metabolism. Installed deterioration obesity, manifested by reliable combined need complex treatment preventive measures earlier stages (first years) reduce atherogenic future.