Lipid-hydrogel films for sustained drug release
نویسندگان
چکیده
منابع مشابه
pH Sensitive Hydrogel Based Acrylic Acid for Controlled Drug Release
Hydrogels, due to their unique potentials such as high-water content and hydrophilicity are interest for the controlled release of drug molecules. The present study aims to create a controlled-release system through the preparation and characterization of hydrogels based on pH-sensitive polymers such as poly (acrylic acid). Poly (acrylic acid), p(AA), hydrogel has been synthesized by radical po...
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Background: Inflammatory bone resorption in periodontitis can lead to tooth loss. Systemic administration of bisphosphonates such as risedronate for preventing bone resorption can cause adverse effects. Alginate hydrogel (ALG) and poly (lactic acid-co-glycolic acid) (PLGA) microparticles have been studied as drug delivery systems for sustained release of drugs. Therefore, the release pattern of...
متن کاملA microparticle/hydrogel combination drug-delivery system for sustained release of retinoids.
PURPOSE To design and develop a drug-delivery system containing a combination of poly(D,L-lactide-co-glycolide) (PLGA) microparticles and alginate hydrogel for sustained release of retinoids to treat retinal blinding diseases that result from an inadequate supply of retinol and generation of 11-cis-retinal. METHODS To study drug release in vivo, either the drug-loaded microparticle-hydrogel c...
متن کاملph sensitive hydrogel based acrylic acid for controlled drug release
hydrogels, due to their unique potentials such as high-water content and hydrophilicity are interest for the controlled release of drug molecules. the present study aims to create a controlled-release system through the preparation and characterization of hydrogels based on ph-sensitive polymers such as poly (acrylic acid). poly (acrylic acid), p(aa), hydrogel has been synthesized by radical po...
متن کاملHydrogel functionalization with DNA aptamers for sustained PDGF-BB release.
We demonstrate that hydrogel functionalization with DNA aptamers can be applied for developing a novel sustained-release system.
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2015
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2015.01.013