Lipid Electrophoresis Patterns in Xanthomatosis

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MR spectroscopy detects lipid peaks in cerebrotendinous xanthomatosis.

CTX is a rare lipid-storage disease. Novel MRS findings from 3 patients, using a short TE, were the presence of lipid peaks at 0.9 and 1.3 ppm in the depth of the cerebellar hemisphere; this might represent an additional marker of disease that is CNS-specific and noninvasive. A decrease in NAA concentration was also detected and attributed to neuroaxonal damage. One patient presented an increas...

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ژورنال

عنوان ژورنال: Proceedings of the Royal Society of Medicine

سال: 1956

ISSN: 0035-9157

DOI: 10.1177/003591575604901229