Lipid-based nanotherapeutics for siRNA delivery
نویسندگان
چکیده
منابع مشابه
Peptide-siRNA nanotherapeutics in arthritis
RNA interference (RNAi) is a process that involves the delivery of small single stranded RNA molecules into mammalian cells, resulting in the sequence-specific cleavage of complementary mRNA and the silencing of specific gene expression. These small RNA molecules called small interfering RNAs (siRNAs) are the focus of intense research due to their potential therapeutic uses in various disease p...
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Since the discovery of the "starburst polymer", later renamed as dendrimer, this class of polymers has gained considerable attention for numerous biomedical applications, due mainly to the unique characteristics of this macromolecule, including its monodispersity, uniformity, and the presence of numerous functionalizable terminal groups. In recent years, dendrimers have been studied extensively...
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ژورنال
عنوان ژورنال: Journal of Internal Medicine
سال: 2010
ISSN: 0954-6820,1365-2796
DOI: 10.1111/j.1365-2796.2009.02189.x