Linkage analysis programs for mapping economical.

Mapping and Linkage Analysis

Bioinformatics is a discipline at the intersection of biology, computer science, information technology andmathematics. It aims at integrating and analysing awealth of biological data with the aim of identifying and assigning a function to each of the parts list of a living organism and understanding the incredibly complex processes that define life at a systems level. It is applied, for exampl...

2LD, GENECOUNTING and HAP: computer programs for linkage disequilibrium analysis

UNLABELLED Computer programs are introduced which calculate pair-wise linkage disequilibrium statistics and conduct haplotype frequency estimation, including X chromosome data, and using a heuristic algorithm to handle multiple genetic markers and missing data. AVAILABILITY Programs 2LD, GENECOUNTING and HAP are available on Internet from http://www.hgmp.mrc.ac.uk/~jzhao and http://www.iop.kc...

Economical Consequences of Johne’s Disease Control Programs

Bayesian analysis of haplotypes for linkage disequilibrium mapping.

Haplotype analysis of disease chromosomes can help identify probable historical recombination events and localize disease mutations. Most available analyses use only marginal and pairwise allele frequency information. We have developed a Bayesian framework that utilizes full haplotype information to overcome various complications such as multiple founders, unphased chromosomes, data contaminati...

Bolck Linkage Disequilibrium Mapping

1. Abstract 2. Introduction 3. Models and methods 3.1. Haplotype block characterization 3.2. Measure of haplotype block LD 3.3. Test statistic and power calculation 3.4. Population genetic model of haplotype block 4. Results 4.1. Haplotype block LD measure 4.2. Power of the haplotype block LD mapping 4.3. Mapping 5. Discussion 6. Appendix 6.1. Appendix A 6.2. Appendix B 6.3. Appendix C 7. Refer...