Linear normalization of MR brain images in pediatric patients with periventricular leukomalacia

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Linear normalization of MR brain images in pediatric patients with periventricular leukomalacia.

The feasibility of linear normalization of child brain images with structural abnormalities due to periventricular leukomalacia (PVL) was assessed in terms of success rate and accuracy of the normalization algorithm. Ten T1-weighted brain images from healthy adult subject and 51 from children (4-11 years of age) were linearly transformed to achieve spatial registration with the standard MNI bra...

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Cerebral visual impairment in periventricular leukomalacia: MR correlation.

PURPOSE To evaluate the involvement of central visual pathways in cases of periventricular leukomalacia, and to correlate the neuroradiologic findings with the degree of visual acuity. METHODS The MR brain examinations of 27 preterm children affected by cerebral palsy resulting from periventricular leukomalacia and without significant ophthalmologic lesions were reviewed retrospectively to se...

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Pontine hypoplasia in children with periventricular leukomalacia.

BACKGROUND AND PURPOSE The brain stem in patients with periventricular leukomalacia (PVL) appears smaller than normal on MR imaging, but few reports have described this feature, and the number of patients has been relatively small. The present study was conducted to examine the hypothesis that the pons in patients with PVL is smaller than normal. MATERIALS AND METHODS Using MR imaging, we exa...

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Neurodevelopmental outcome in children with periventricular leukomalacia.

The purpose of this study was to question the correlation of different grades of periventricular leukomalacia (PVL) and subsequent neurodevelopmental outcome. In a prospective study we followed 52 preterm infants. Infants were divided into three groups according to their cranial ultrasound findings of PVL (De Vries classification). Seventeen children had PVL 1, 20 children had PVL 2, and 15 chi...

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Animal Models of Periventricular Leukomalacia

Periventricular leukomalacia, specifically characterized as white matter injury, in neonates is strongly associated with the damage of pre-myelinating oligodendrocytes. Clinical data suggest that hypoxia-ischemia during delivery and intrauterine or neonatal infection-inflammation are important factors in the etiology of periventricular leukomalacia including cerebral palsy, a serious case exhib...

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ژورنال

عنوان ژورنال: NeuroImage

سال: 2007

ISSN: 1053-8119

DOI: 10.1016/j.neuroimage.2006.12.037