منابع مشابه
Mitochondria take center stage
Mitochondria are the ubiquitous power units of animal cells, responsible for “oxphos,” the aerobic synthesis of most of the ATP that serves as the common coin of cellular metabolism. To perform their primary task of oxidative phosphorylation and to manage many secondary tasks, mitochondria use more than 1,000 proteins, of which fewer than 100 are involved directly in oxidative phosphorylation. ...
متن کاملCentrioles take center stage
Centrioles are among the most beautiful and mysterious of all cell organelles. Although the ultrastructure of centrioles has been studied in great detail ever since the advent of electron microscopy, these studies raised as many questions as they answered, and for a long time both the function and mode of duplication of centrioles remained controversial. It is now clear that centrioles play an ...
متن کاملMetabolic Homeostasis: HDACs Take Center Stage
Hormonal regulation of glucose and lipid metabolism is pivotal for metabolic homeostasis and energy balance. Two studies in this issue of Cell (Mihaylova et al., 2011 and Wang et al., 2011) introduce a new conserved signaling mechanism controlling catabolic gene expression: class IIa histone deacetylases (HDACs) regulate Foxo activity in Drosophila and mice.
متن کاملRho and Rac Take Center Stage
Many features of cell behavior are regulated by Rho family GTPases, but the most profound effects of these proteins are on the actin cytoskeleton and it was these that first drew attention to this family of signaling proteins. Focusing on Rho and Rac, we will discuss how their effectors regulate the actin cytoskeleton. We will describe how the activity of Rho proteins is regulated downstream fr...
متن کاملMembrane proteins take center stage in Frankfurt.
Biological membranes are dynamic frontiers whose molecules must delicately balance the needs for compartmentalization and communication, and the gap between the vital significance of transport and signaling through membranes and our poor understanding of the precise functionality of these processes is daunting. However, a recent conference highlighted promising progress in the field, particular...
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ژورنال
عنوان ژورنال: Mechanical Engineering
سال: 1998
ISSN: 0025-6501,1943-5649
DOI: 10.1115/1.1998-mar-5