منابع مشابه
A life without worms
Worms have co-evolved with humans over millions of years. To survive, they manipulate host systems by modulating immune responses so that they cause (in the majority of hosts) relatively subtle harm. Anthelminthic treatment has been promoted as a measure for averting worm specific pathology and to mitigate subtle morbidities which may include effects on anaemia, growth, cognitive function and e...
متن کاملWorms, Life and Death
I never expected to spend most of my life studying worms. However, when it came time for me to choose an area for my postdoctoral research, I was intrigued both with the problems of neurobiology and with the approaches of genetics. Having heard that a new “genetic organism” with a remarkably simple nervous system was being explored by Sydney Brenner – the microscopic soil nematode Caenorhabditi...
متن کاملSKNy Worms and Long Life
Interactions between insulin signaling and stress-response pathways can markedly impact life span. In this issue, Tullet et al. (2008) demonstrate that the worm homolog of Nrf2, called SKN-1, a transcription factor that switches on expression of antioxidant genes, is an important component of such signaling interactions.
متن کاملCommentary: Twins, worms and life course epidemiology.
Scientists can be remarkably flexible when investigating the nature of health and survival, taking advantage of populations from roundworms to humans to gain insight. Yet, flexibility can foster concern over generalizability. In this issue of IJE, Öberg et al. provide evidence on the generalizability of findings with twins, one of epidemiology’s most popular special populations, by showing that...
متن کاملNobel lecture. Worms, life and death.
I never expected to spend most of my life studying worms. However, when it became time for me to choose an area for my postdoctoral research, I was intrigued both with the problems of neurobiology and with the approaches of genetics. Having heard that a new ‘‘genetic organism’’ with a remarkably simple nervous system was being explored by Sydney Brenner—the microscopic soil nematode Caenorhabdi...
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ژورنال
عنوان ژورنال: Chemistry & Biology
سال: 2000
ISSN: 1074-5521
DOI: 10.1016/s1074-5521(00)00026-0