Libman-Sacks Endocarditis: Detection, Characterization, and Clinical Correlates by Three-Dimensional Transesophageal Echocardiography

Mitral valve Libman-Sacks endocarditis visualized by real time three-dimensional transesophageal echocardiography.

Libman-Sacks endocarditis (LSE) is a common manifestation of valve disease in antiphospholipid syndrome. Mitral valve LSE is characterized by verrucous vegetations on the atrial surfaces of valve leaflets. In this report, mitral valve LSE was visualized by real time 3D transesophageal echocardiography (TEE). 3D TEE provides a unique en face view of the mitral valve akin to a surgical or autopsy...

Libman-Sacks Endocarditis

In 1924 Libman and Sacks published an account of atypical, sterile, verrucous vegetations on the heart in systemic lupus erythematosus (SLE). [1] Clusters of verrucae, looking like mulberries, were described on the ventricular surface of the posterior leaflet of the mitral valve and found at postmortem. The leaflet and the chordae tendinae are often adherent to the endocardium of the ventricula...

Real-time three-dimensional echocardiography in evaluating Libman-Sacks vegetations.

Libman-Sacks endocarditis, characterized by sterile fibrofibrinous vegetations that have the potential to develop anywhere on the endocardial surface, was originally reported in 1924. The mitral valve is most commonly affected, followed by the aortic valve, whereas tricuspid and pulmonary valves are seldom involved. Libman-Sacks vegetations can be found in approximately 1 of 10 patients with sy...

Three-dimensional transesophageal echocardiography of pacemaker endocarditis.

Libman-Sacks endocarditis and oral anticoagulation.

The patient is a 34-year-old female with systemic lupus erythematosus and secondary antiphospholipid antibody syndrome, who evolved with convulsive crises, partially controlled with an anticonvulsant, and auscultation of a cardiac murmur, whose investigation showed the presence of a mitral valve vegetation. Once the diagnosis of Libman-Sacks endocarditis was established, therapy with warfarin s...