LFA-1-dependent lipid raft recruitment of DNAM-1 (CD226) in CD4+ T cell
نویسندگان
چکیده
منابع مشابه
Requirement of the serine at residue 329 for lipid raft recruitment of DNAM-1 (CD226).
Upon antigen recognition by the TCR, leukocyte function-associated antigen-1 (LFA-1) physically associates with the leukocyte adhesion molecule DNAM-1 (CD226), for which the serine phosphorylation at residue 329 (S329) of DNAM-1 plays a critical role. The TCR-mediated signal also induces the formation of the immunological synapse (IS), in which lipid raft-associated molecules, including LFA-1, ...
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ژورنال
عنوان ژورنال: International Immunology
سال: 2006
ISSN: 1460-2377,0953-8178
DOI: 10.1093/intimm/dxl031