Leukocyte Count and Intracerebral Hemorrhage Expansion
نویسندگان
چکیده
منابع مشابه
Leukocyte Count and Intracerebral Hemorrhage Expansion.
BACKGROUND AND PURPOSE Acute leukocytosis is a well-established response to intracerebral hemorrhage (ICH). Leukocytes, because of their interaction with platelets and coagulation factors, may in turn play a role in hemostasis. We investigated whether admission leukocytosis was associated with reduced bleeding after acute ICH. METHODS Consecutive patients with primary ICH were prospectively c...
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Intracerebral hemorrhage (ICH), the most devastating form of stroke, has no specific therapy proven to improve outcome by randomized controlled trial. Location and baseline hematoma volume are strong predictors of mortality, but are nonmodifiable by the time of diagnosis. Expansion of the initial hematoma is a further marker of poor prognosis that may be at least partly preventable. Several ris...
متن کامل“Monocyte Count and 30-Day Case Fatality in Intracerebral Hemorrhage”
Response to Letter Regarding Article, “Monocyte Count and 30-Day Case Fatality in Intracerebral Hemorrhage” We appreciate the letter from Hu et al on our recent publication.2 Our response addresses 2 points raised in their letter: (1) evidence that infiltrating neutrophils (not monocytes) play a role in intracerebral hemorrhage (ICH)–induced brain injury and (2) their multivariate logistic regr...
متن کاملApolipoprotein E genotype predicts hematoma expansion in lobar intracerebral hemorrhage.
BACKGROUND AND PURPOSE Hematoma volume is the most potent predictor of outcome in spontaneous intracerebral hemorrhage (ICH), and hematoma expansion after hospital presentation occurs in up to 40% of individuals. Among patients with lobar ICH, the apolipoprotein E (APOE) ε2 allele predicts larger hematoma volumes at presentation. We investigated whether the ε2 allele also identifies individuals...
متن کاملDefining hematoma expansion in intracerebral hemorrhage: relationship with patient outcomes.
BACKGROUND Hematoma expansion (HE) is a surrogate marker in intracerebral hemorrhage (ICH) trials. However, the amount of HE necessary to produce poor outcomes in an individual is unclear; there is no agreement on a clinically meaningful definition of HE. We compared commonly used definitions of HE in their ability to predict poor outcome as defined by various cutpoints on the modified Rankin S...
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ژورنال
عنوان ژورنال: Stroke
سال: 2016
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.116.013176