Leukocyte adhesion deficiency type I in a mixed-breed dog

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Leukocyte Adhesion Deficiency Type 1 Presenting as Leukemoid Reaction

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Periodontal manifestation of leukocyte adhesion deficiency type I.

BACKGROUND Leukocyte adhesion deficiency type I (LAD-I) is an autosomal recessive immunodeficiency disorder characterized by defects in the integrin receptors of white blood cells that lead to impaired adhesion and chemotaxis. Affected patients are susceptible to recurrent bacterial and fungal infections, impaired pus formation, delayed wound healing, and periodontitis. METHODS A case of gene...

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Clinical profile of leukocyte adhesion deficiency type I.

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leukocyte adhesion deficiency type 1 presenting as leukemoid reaction

the hallmarks of leukocyte adhesion deficiency (lad) are defects in the leukocyte adhesion process, marked leukocytosis and recurrent infections. these molecular and clinical manifestations result from an impaired step in the inflammatory process, namely, the emigration of leukocytes from the blood vessels to sites of infection, which requires adhesion of leukocytes to the endothelium. over las...

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ژورنال

عنوان ژورنال: Journal of Veterinary Diagnostic Investigation

سال: 2013

ISSN: 1040-6387,1943-4936

DOI: 10.1177/1040638713478814