LEUKEMIA-ASSOCIATED TRANSPLANTATION ANTIGENS RELATED TO MURINE LEUKEMIA VIRUS
نویسندگان
چکیده
منابع مشابه
Leukemia-associated Transplantation Antigens Related to Murine Leukemia Virus
Two BALB radiation leukemias are strongly rejected by hybrids of BALB with certain other mouse strains, although BALB mice themselves exhibit no detectable resistance whatever. Hybrids immunized with progressively increased inocula are resistant to 200 x 10(6) or more leukemia cells; their serum is cytotoxic for the leukemia cells in vitro and protects BALB mice against challenge with these BAL...
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It is now well established that viruses of the murine leukemia virus (MuLV)' group are present ifi all m i ~ (1, 2) and that viral genetic sequences are present as chromosomal DNA (3-5). The expression of this genetic material, as virus particles or viral antigens, differs markedly between strains of mice, both with regard to the age at which the expression occurs (6-8) and the spectrum of biol...
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ابزارهای گوناگونی به منظور انتقال ژن به سلول های یوکاریوتی توسعه یافته اند، در میان آن ها، کارایی ویروس های rna دار متعلق به خانواده رتروویریده به دلیل الحاق پایدار ژنوم خود در کروموزوم های میزبان بالاتر است. ویروس لوکمی موش (mlv) شناخته شده ترین عضو جنس اورتورتروویرینا از گامارتروویروس ها است. ناقل ویروسی بر پایه mlv تنها قادر به بیان ژن های خارجی در سلول های در حال تقسیم میتوز می باشد، که بیا...
15 صفحه اولIn vitro studies of cell-mediated immunity to Moloney murine leukemia virus and Moloney leukemia-associated surface antigens.
Cell-mediated immunity to Moloney murine leukemia virus (M-MuLV) and to tumor-associated surface antigens of leukemia cells induced by the virus was studied with an in vitro migration inhibition factor assay. Spleen cells of C57BL/6N mice at Day 14 following inoculation with Moloney murine sarcoma virus, produced migration inhibition factor in response to M-MuLV. The Moloney murine sarcoma viru...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1973
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.138.3.593