منابع مشابه
Glyco-Forum section
The discipline of glycobiology contributes to our understanding of human health and disease through research, most of which is published in peer-reviewed scientific journals. Recently, legitimate discoveries in glycobiology have been used as marketing tools to help sell plant extracts termed “glyconutrients.” The glyconutrient industry has a worldwide sales force of over half a million people a...
متن کاملGlyco-Forum section Dietary glucosamine under question
Annual sales of glucosamine as a neutraceutical for affecting cartilage in treatment of osteoarthritis are close to a billion dollars, but recent clinical studies have currently raised severe criticism regarding its functional value. Additional doubts can be raised by the knowledge of the well-defined cellular steps in glucosamine formation and production of glycosaminoglycans such as chondroit...
متن کاملGlyco-Forum section For intra-articular delivery of chondroitin sulfate
So far, there is no efficient treatment that could stop the pathological process of osteoarthritis (OA), and the management of the disease is mainly based on the alleviation of clinical symptoms by nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesics compounds. However, some natural products have been proposed as symptomatic treatments, and named symptomatic slow acting disease modifyin...
متن کاملGlyco-Forum section Natural ligands for CD33-related Siglecs?
Finding natural ligands involved in protein–protein interactions is relatively easy, and false-positives are rare. In contrast, the natural ligands for glycan-binding proteins (GBPs) can be quite elusive, and artifacts are common. For example, it took almost 10 years from the detection of P-selectin’s glycan binding properties (Moore et al. 1991) to reach the definitive conclusion that a certai...
متن کاملLetter to the Glyco-Forum: catalytic domains of glycosyltransferases with 'add-on' domains.
Glycosyltransferases (GTs) belong to a large family of enzymes that are involved in the synthesis of oligosaccharide moieties of glycoproteins, glycolipids, and proteoglycans and have been assembled in a CAZy database (http://www.cazy.org). In the eukaryotic cells, most of these enzymes are Golgiresident type II membrane proteins with a cytoplasmic domain, a transmembrane domain, and a stem reg...
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ژورنال
عنوان ژورنال: Glycobiology
سال: 1996
ISSN: 0959-6658,1460-2423
DOI: 10.1093/glycob/6.7.647-a