Letter: Early detection of growth hormone deficiency.

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Catch-up growth in early treated patients with growth hormone deficiency. Dutch Growth Hormone Working Group.

Catch-up growth of 26 children with growth hormone deficiency during four years of growth hormone treatment, which was started young (< 3 years), was compared with that of 16 children with coeliac disease on a gluten free diet. In children with growth hormone deficiency mean (SD) height SD score increased from -4.3 (1.8) to -1.9 (1.4) and in patients with coeliac disease from -1.8 (0.9) to -0.1...

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Early-onset idiopathic growth hormone deficiency within KIGS.

Growth hormone (GH) deficiency is normally diagnosed when the affected child is between 6 and 8 years of age and a lack of normal growth first becomes noticeable. Some patients, however, are diagnosed as being GH deficient at a relatively young age (<2 years). These patients differ from the later-diagnosed patients in terms of their background, their characteristics of GH deficiency (GHD) and t...

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Adult Growth Hormone Deficiency

Adult growth hormone deficiency (AGHD) is an heterogeneous clinical entity characterized by increased cardiovascular morbidity and mortality, alterations in body composition, osteoporosis and impaired quality of life. In order to characterize higher risk subpopulations we studied 77 patients with AGHD, 35 with childhood onset (AGHD-CO): CA 18-44 yr.; 13 females and 22 males, and 42 with adult o...

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Adult growth hormone deficiency.

Growth hormone (GH) has an important physiological role in adulthood.1–3 Before the 1980s anecdotal reports suggested that patients lacking GH experienced symptoms of increased fatigue and low mood, features that improved with GH replacement.4 Long-term replacement was not considered because of the lack of availability of cadaveric GH. With the development of recombinant GH in the mid-1980s, in...

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Aetiology of growth hormone deficiency.

A retrospective analysis was performed in an attempt to identify perinatal risk factors for the development of growth hormone deficiency. More of the affected children were boys, and their birth weights were significantly lower than those of the national average; there were also considerably more preterm and post-term deliveries among boys.

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ژورنال

عنوان ژورنال: BMJ

سال: 1976

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.6011.709-a