منابع مشابه
Let’s Not Forget Validation
As we are moving from a traditional software development process to a new development paradigm where the process it largely driven by tools and automation, new challenges for verification and validation (V&V) emerge. Productivity improvements will in this new paradigm be achieved through reduced emphasis on testing of implementations, increased reliance on automated analysis tools applied in th...
متن کاملLet’s not forget tautomers
A compound exhibits tautomerism if it can be represented by two structures that are related by an intramolecular movement of hydrogen from one atom to another. The different tautomers of a molecule usually have different molecular fingerprints, hydrophobicities and pKa's as well as different 3D shape and electrostatic properties; additionally, proteins frequently preferentially bind a tautomer ...
متن کاملThe Forget-me-not Process
We introduce the Forget-me-not Process, an efficient, non-parametric metaalgorithm for online probabilistic sequence prediction for piecewise stationary, repeating sources. Our method works by taking a Bayesian approach to partitioning a stream of data into postulated task-specific segments, while simultaneously building a model for each task. We provide regret guarantees with respect to piecew...
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ژورنال
عنوان ژورنال: BMJ
سال: 2020
ISSN: 1756-1833
DOI: 10.1136/bmj.m2167