Let‐7 and miR‐125 cooperate to prime progenitors for astrogliogenesis
نویسندگان
چکیده
منابع مشابه
Let-7 and miR-125 cooperate to prime progenitors for astrogliogenesis.
The molecular basis of astrocyte differentiation and maturation is poorly understood. As microRNAs have important roles in cell fate transitions, we set out to study their function during the glial progenitor cell (GPC) to astrocyte transition. Inducible deletion of all canonical microRNAs in GPCs in vitro led to a block in the differentiation to astrocytes. In an unbiased screen, the reintrodu...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2015
ISSN: 0261-4189,1460-2075
DOI: 10.15252/embj.201489504