Leptin-mediated regulation of MT1-MMP localization is KIF1B dependent and enhances gastric cancer cell invasion
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چکیده
منابع مشابه
KIF1B promotes glioma migration and invasion via cell surface localization of MT1-MMP.
Malignant glioma is notorious for its aggressiveness and poor prognosis, and the invasiveness of glioma cells is the major obstacle. Accumulating evidence indicates that kinesin superfamily proteins (KIFs) may play key roles in tumor invasiveness, but the mechanisms remained unresolved. Our previous study demonstrated that membrane type 1-matrix metalloproteinase (MT1-MMP) was involved in Kines...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2013
ISSN: 1460-2180,0143-3334
DOI: 10.1093/carcin/bgt028