Leptin and energy expenditure

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Leptin and energy expenditure.

PURPOSE OF REVIEW A fundamental advance in our understanding of endocrine control of energy balance and body weight came with the discovery of the adipocyte-derived hormone leptin. The leptin pathway appeared to be the long-sought peripheral signal pathway from the adipose tissue to the brain involved in the regulation of feeding and energy balance. RECENT FINDINGS Initially, leptin was consi...

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Serum leptin and energy expenditure in children.

Leptin has been hypothesized to play an important role in energy balance by affecting both energy intake and energy expenditure. The purpose of our study was to determine the relationship between fasting serum leptin concentrations and measures of energy expenditure in prepubertal children. We measured total energy expenditure (TEE; by the doubly labeled water technique), resting energy expendi...

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The leptin-dependent and -independent melanocortin signaling system: regulation of feeding and energy expenditure.

The brain hypothalamus coordinates extra-hypothalamic regions to maintain energy homeostasis through the regulation of food intake and energy expenditure. A number of anorexigenic and orexigenic molecules in the hypothalamic nuclei participate in the control of energy homeostasis. Leptin and pro-opiomelanocortin (POMC)-derived alpha-melanocyte-stimulating hormone are key anorectic molecules, an...

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Contribution of Leptin to Energy Expenditure and Glucose Metabolism in Fasting

Leptin regulates energy homeostasis and is involved in glucose metabolism. It is known that leptin plays an important role in neuroendocrine response to fasting; therefore, the essential role of leptin may be the response to starvation. In this study, we examined the role of leptin in energy expenditure and glucose metabolism in fasting. Methods: C57BL/6 and leptin mutant ob/ob mice were fasted...

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Effect of energy expenditure and training status on leptin response to sub-maximal cycling.

We examined the leptin response and related hormones during and after two sub-maximal exercise protocols in trained and untrained subjects. During this study, plasma concentrations of leptin [Lep], insulin [I], cortisol [C], growth hormone [GH], glucose [G] and lactate [La] were measured. 7 elite volleyball trained players (TR) and 7 untrained (UTR) subjects (percent body fat: 13.2 ± 1.8 versus...

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ژورنال

عنوان ژورنال: Current Opinion in Clinical Nutrition and Metabolic Care

سال: 2004

ISSN: 1363-1950

DOI: 10.1097/00075197-200411000-00007