Leaving the midline

Leaving the Past Behind

There is considerable interest from the wider scientific community in the heritability of epigenetic states across generations, and this has arisen as a result of a series of studies in mice [1,2], flies [3], plants [4,5], and yeast [6] over the past decade. These studies have identified genetic elements at which epigenetic states appear to be inherited through meiosis. The Lamarckian implicati...

Leaving the sheltered workshop

Leaving the Banquet

The offerings in this, my last issue as Editor of Addiction Science & Clinical Practice, reinforce my feeling of stepping away from a banquet that has many rich courses still to come. In this final issue produced by NIDA: • Drs. Manoranjan D’Souza and Athina Markou review what researchers have discovered about how nicotine affects brain function to produce dependence, and examine the prospects ...

Leaving the Span

We discuss a simple sparse linear problem that is hard to learn with any algorithm that uses a linear combination of the training instances as its weight vector. The hardness holds even if we allow the learner to embed the instances into any higher dimensional feature space (and use a kernel function to define the dot product between the embedded instances). These algorithms are inherently limi...

Leaving the Hospital

As the doors glide shut behind me, the world fl ares back into being— I exist again, recover myself, sunlight undimmed by dark panes, the heat on my arms the earth’s breath. The wind tongues me to my feet like a doe licking clean her newborn fawn. At my back, days measured by vital signs, my mouth opened and arm extended, the nighttime cries of a man withered child-size by cancer, and the bells...